Cancer

Disease with the fibrokistik In the women adenosis, fibroadenoma and fibrosis, there is no increased risk of breast cancer occurrence. In hiperplasis and papiloma, slightly increased the risk 1.5 to 2 times. Meanwhile, in the hiperplasia atipik, the risk increased to 5 times.

Obesity There is a positive relationship between body weight and body shape with breast cancer in women post-off. Variations of the frequency of cancer in these countries in West and not the West and frequency changes after the migration indicates that there is the influence of diet on the occurrence of this malignancy.

Consumption of fat consumption is estimated to be fat as a risk factor of the occurrence of breast cancer. Willet et al., Prospective study conducted during the 8 years the consumption of fat and fiber in conjunction with the risk of breast cancer in women age 34 to 59 years old.

Radiation Exposure with ionization radiation during or after the occurrence of pubertas increase the risk of breast cancer. From several studies conducted concluded that the risk of cancer related to radiation dose with the Linear and age when the occurrence of exposure.

Family history and genetic factors, family history is an important component in the history of the screening will be conducted for breast cancer. There is a growing risk of violence in this family of women who suffer breast cancer. In genetic studies found that breast cancer associated with certain genes. When there is a BRCA 1, a suseptibilitas breast cancer genes, the probability for breast cancer is 60% in the age of 50 years and 85% in the age of 70 years.

Stadium cancer

After each faktot T,. N, M is established, the third factor is then merged and acquired stadium cancer as follows:

* Stadium 0: T0 N0 M0
* Stadium 1: T1 N0 M0
* Stadium II A: T0 N1 M0 / T1 N1 M0 / T2 N0 M0
* Stadium II B: T2 N1 M0 / T3 N0 M0
* Stadium III A: T0 N2 M0 / T1 N2 M0 / T2 N2 M0 / T3 N1 M0 / T2 N2 M0
* Stadium III B: T4 N0 M0 / T4 N1 M0 / T4 N2 M0
* Stadium III C: Each T N3 M0
* IV Stadium: Each Each T-N-M1

In breast cancer, TNM assessment as follows:

In breast cancer, TNM assessment as follows:

• T (tumor size), the size of the tumor:

T * 0: not found the primary tumor
T * 1: the size of the tumor diameter of 2 cm or less
* Q 2: the size of the tumor diameter of between 2-5 cm
* Q 3: diameter of the tumor size> 5 cm
* Q 4: does the size of tumors, but there is the spread to the skin or chest wall or both, can be a sore, ederma or swelling, skin redness or a breast benjolan small skin tumors outside the main

• N (node), the regional lymph glands (KGB):

N * 0: there is no Metastasis in the armpit at the regional KGB / aksilla
N * 1: there Metastasis to the KGB aksilla that can still be moved
N * 2: there Metastasis to the KGB aksilla difficult moved
N * 3: there Metastasis to the KGB in the clavicle (supraclavicula) or the KGB in the mammary International in the bone near the sternum

• M (Metastasis), the spread of far:

* M x: Metastasis far can not be assessed
* M 0: there is not much Metastasis
M * 1: there are far Metastasis

Breast cancer

Breast cancer is breast cancer on the network. This is the most common type of cancer that women suffer. Men can also contract breast cancer, although the probability is smaller than 1 in 1000. The most common treatment is surgery and, if necessary followed by chemotherapy and radiation.

Cancer is a condition in which cells have lost control and the normal mechanisms, so that growth is not normal, fast and not restrained. (http://www.mediasehat.com/utama07.php)

Breast cancer (Carcinoma mammae) is a malignant disease that neoplasma derived from the parenchyma. This disease by Word Health Organization (WHO) to be included in the International Classification of Diseases (ICD) with the code number 17 (http://www.tempo.co.id/medika/arsip/082002/pus-3.htm

Patofisiologi
Tuesday transformation-formed cancer cells from normal cells in a complex process called transformation, which consists of the initiation and promotion phase.

at the initiation stage occurs a change in the genetic material of cells that provoke the cells to become malignant. Changes in the genetic material of cells is caused by an agent called Carcinogen, which can form chemicals, viruses, radiation (irradiation) or sunlight.

but not all cells have the same sensitivity to a Carcinogen. aberration in the genetic material of cells or other called promoter, causing the cells more vulnerable to a Carcinogen. even physical interference menahunpun can make cells become more sensitive to experience a malignancy.

on the stage of the campaign, a cell that has experienced a change initiatives will become malignant.
Cells not pass through initiation stage will not be affected by the campaign. because it required several factors to the occurrence of violence (a combination of the sensitive cells and a Carcinogen).

Stadium Stadium cancer is a disease condition results from a doctor diagnose a disease when the cancer patient who suffered, is the extent to which the level of the spread of cancer is better to the organ or tissue around and far into the spread of the Stadium is only known in the malignant tumor or cancer and not in the tumor tame.

To determine a stadium, should be conducted clinical examination and inspection by the other supporting histopatologi or PA, X-rays, USG, and, if possible with the CT scan, etc. scintigrafi. Many ways to determine the stadium, but for many the most current stadium cancer is based on the TNM classification system recommended by the UICC (International Union Against Cancer from the WHO or the World Health Organization) / AJCC (American Joint Committee on cancer sponsored by the American Cancer Society and the American College of Surgeons).

In the TNM system of assessed three main factors, namely "Q", namely tumor size or tumor size, "N", namely node or regional lymph glands and "M" Metastasis is the spread or distant. The third factor Q, N, M votes either be done before clinical operations, also conducted after the operation and inspection histopatologi (PA)